arthritis rheumatoid doctors No Further a Mystery

The immune system of many people is failing to distinguish between healthy cells from invading microorganisms. This is leading to more suffering around the world. They are now being attacked by defenses against disease that used to protect the body from infection.




International research efforts are intensifying to counter this trend. A prime example is the London Francis Crick Institute initiative in which James Lee and Carola Vinesa two experts from around the world in the area, have formed separate research groups that will assist in determining the exact reasons behind autoimmune diseases.


Lee explained that autoimmune diseases have been on the rise since the past 40 years in the West. We are seeing some emerge in nations that have never experienced the disease before.


For example, the biggest recent rise in cases of inflammatory bowel disease has occurred in the Middle East and east Asia. They'd never seen the disease prior to.


Type 1 diabetes, multiple sclerosis IBD and rheumatoidarthitis all are auto-immune diseases. In all cases your immune system gets confused and shifts to healthy tissue instead of the pathogens that cause infection.


At least 4 million people suffering from autoimmune diseases in the UK, and some suffer from multiple. Globally, it's estimated that the incidence of autoimmune diseases is rising at a rate of between 3 to 9 percent per year. The majority of scientists believe that environmental factors play a key factor in this growth.


Lee who worked previously in Cambridge University, said that the human genetics of humans has not changed over the past decades. Therefore, something is changing within our bodies that could increase our vulnerability to developing an autoimmune disease.


Vinuesa agreed with the idea having worked previously in the Australian National University. She noted that diet changes were happening when more nations adopted Western-style eating habits, and more people were buying fast food items.


Vinuesa states that many fast-food products lack essential ingredients such as fibre. This could alter your microbiome, which is the collection micro-organisms found in our bodies and which play an important part in regulating various bodily functions.


These changes in microbiomes lead to autoimmune diseases. There are over 100 kinds.


The two scientists also stressed that every person is susceptible to these diseases that include celiac, Lupus, and other conditions, such as celiac, which trigger inflammation and swelling and may cause severe damage to the organs of various.


"If you don't possess a particular genetic susceptibility it is unlikely that you will develop an auto-immune disease, no matter how many Big Macs you consume," said Vinuesa. "We have no way to stop the rapid growth of fast-food outlets all over the world. Instead we're trying to unravel the genetic causes that cause the development of autoimmune diseases, and makes some people susceptible but others not. We are trying to address the issue at the level of."


The advancement of technology allows us to identify tiny differences in DNA across large populations of people. This is how it's possible to identify the common genetic patterns of patients with an auto-immune disease.


Lee stated that up until recent, we didn't have the tools necessary to sequence DNA. Now, we're able to do it and it has changed everything. When I began my studies, we were aware of half a dozen DNA variants which were responsible for triggering an inflammatory bowel disease. Now, we know more than Read More 250.


Lee and Vinuesa focus their energies on this kind of work. They seek to understand more about genetic pathways that are involved and discover the root causes of diverse diseases they study. If you look at some auto-immune diseases like, lupus - it has been made clear that there are numerous different variants of themthat could be caused by different genetic pathways, Vinuesa explained. This could have an adverse influence on your ability find the right treatment.


There are a lot of new therapies that are likely to be beneficial, but we don’t have the right patients. Actually we don't have the data we require to determine if patients have the same condition. This is the reason why research on autoimmune disease has become a major focus. In order to provide the appropriate treatment, we Click here have to understand how to categorize patients.


Lee stated that the rising incidence of autoimmune diseases around the globe mean that the development of new therapies and medicines is needed now more than ever before. It's impossible to cure autoimmune diseases. This happens when people are young and trying to finish their education and get their first job, and have families.


This means that more patients will require regular injections for the remainder of their lives. This is a stressful time for patients, and can put an huge strain on the health system. It is urgent that we find new, more effective treatments.


Rheumatoid arthritis is an auto-immune disease. It is caused by the immune system attacks healthy body tissues. However, it's not clear what triggers it.


Your immune system normally makes antibodies that attack viruses and bacteria, helping to fight infections.


Rheumatoid arthritis is a disease that affects your immune system and sends antibodies to your joints. They attack the joint tissue around the joint.


This causes the thin synovium layer of cells that surround your joints to become swollen. In addition, it releases chemicals that can cause injuries to the area.


bones

Cartilage, the connective tissue between bones.

Tendons are connective tissue between bone and muscles.

Ligaments - The ligaments - The tissue that connects bone to cartilage

Rheumatoid arthritis is treatable but it is not managed. The chemicals that cause it cause joints to become unbalanced and distorted. It could eventually cause the destruction of the joint.


There are many theories about how the immune system can attack the joints have been suggested, such as an infection as an underlying cause, however none of them has been proved.

Possible risk factors

There are many things that can increase your chances of developing rheumatoid arthritis including:


You can inherit it from your genes. While there are indicators that suggest that rheumatoidarthritis could be passed down the generations however, the odds of getting it are very low since genes play a minor role in the condition.

The condition is more prevalent among women than in men. This may be due to estrogen effects, but this isn't confirmed.

There is evidence that smokers are at greater chance of developing rheumatoid arthritis.